Quick Start

Get started with a simple API call:

curl -X POST https://api.proteinclassifier.com/v1/classify \
  -H "X-API-Key: your_key_here" \
  -H "Content-Type: application/json" \
  -d '{
    "sequences": [
      {"id": "protein1", "sequence": "MKVLWAASLLLLASAARA"}
    ]
  }'

View Full API Documentation →

Why Choose Our Classifier?

✅

Production-Ready API

Reliable, scalable infrastructure for high-throughput screening

✅

No ML Overhead

Pure biophysics-based approach - fast and interpretable

✅

Bulk Processing Support

Process up to 50 sequences per request efficiently

✅

Free Tier for Research

1000 sequences per day at no cost for academic use

✅

Open Methodology

Transparent validation and scientific approach

✅

Fast Response Times

<50ms per sequence, <500ms for 50-sequence batches

Performance Metrics

Overall Accuracy

84.52%

k=5 optimal threshold

Precision (Structured)

88.01%

Low false positives

Recall (Disordered)

83.13%

Identifies disorder well

F1-Score (DisProt)

80.12%

Balanced performance

Processing Speed

<50ms

Single sequence

Batch Processing

<500ms

50 sequences

Learn About Our Methodology →

Perfect For

High-Throughput Screening

Process thousands of sequences quickly for proteome-wide disorder analysis.

Pipeline Integration

Easy API integration into bioinformatics workflows and automation tools.

Pre-Filtering

Fast initial screening before expensive structural prediction methods.

Research & Education

Transparent methodology suitable for academic research and teaching.

Rigorous Validation

Homology-Aware Cross-Validation: >75% accuracy with no sequence similarity leakage (MMseqs2 clustering)

MobiDB Independent Test: >70% accuracy on external validation dataset

Label-Shuffle Control: ~50% accuracy (proves learning vs. random chance)

Statistical Significance: Narrow bootstrap confidence intervals demonstrate reliable performance

View Detailed Validation Results →

Ready to Get Started?

Join researchers using our API for protein disorder prediction

Get Your API Key View Documentation